Terns Pharmaceuticals, Inc.

1065 East Hillsdale Blvd.

Suite 100

Foster City, California 94404

February 8, 2023

VIA EDGAR SUBMISSION

U.S. Securities and Exchange Commission

Division of Corporation Finance, Office of Life Sciences

100 F Street, N.E.

Washington, D.C. 20549

Attention: Cindy Polynice

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Terns Pharmaceuticals, Inc. hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-269508), so that it may become effective at 4:00 p.m., Eastern time, on February 10, 2023, or as soon as practicable thereafter, or at such later time as the Registrant or its counsel may orally request via telephone call to the staff.